Poster Presentations

The Globalization of Pharmaceutics Education Network (GPEN) Executive Committee is pleased to showcase the outstanding poster abstracts received at the 12th biennial GPEN conference in Singapore. Please click the respective presentation code for a copy of the abstract.

Show or Hide all events

Poster presentations on Thu, 27th Sep

CodeTitleAuthor and affiliation
A1Development of iRGD conjugated semifluorinated nanoassemblies for targeted drug delivery to solid tumors
Abstract
Montira TANGSANGASAKSRI, University of Wisconsin-Madison
A2Developing chitosan nanoparticles loaded with scutellarin/ 2-hydroxypropyl-beta-cyclodextrin inclusion complexes for treatment of Alzheimer's Disease
Abstract
Li ZHANG, National University of Singapore
A3Photochemical internalization of targeted nanoparticles for the intracellular delivery of a cytotoxic protein.
Abstract
Lucía Amine MARTÍNEZ JOTHAR, Utrecht University
A4Formation and investigation of high-aspect ratio polymeric nanocapsules via vesicle templation with RAFT polymerization and their interactions with cells
Abstract
Yunxin XIAO, Monash University
A5Novel polymeric micelles for siRNA delivery
Abstract
Franck MARQUET, University of Geneva
A6Polymeric nanocarriers for intravitreal delivery
Abstract
Vijayabhaskarreddy JUNNUTHULA, University of Helsinki
A7Intraperitoneal delivery of neutron activatable mesoporous silica nanoparticles for the treatment of ovarian cancer peritoneal metastasis
Abstract
Derek HARGROVE, University of Connecticut
A8Development of exosome assembly formed by utilization of DNA hybridization and its application for cancer vaccine
Abstract
Akihiro MATSUMOTO, Kyoto University
A9Bioinspired cell-derived nanovesicles: a novel class of drug delivery systems
Abstract
Yub Raj NEUPANE, National University of Singapore
A10Phytantriol modified with DSPE-PEG2000: a temperature-responsive lipid-based nanomaterials for on-demand drug delivery
Abstract
Xiaohan SUN, Monash University
A11Particle design of porous PLGA microparticles encapsulating poor water-soluble drug as a novel inhalation formulation of lung cancer
Abstract
Miho KOMATSU, Nagoya City University
A12Modification of cationic solid lipid nanoparticles with hyaluronic acid to overcome multi drug resistance
Abstract
Sang Eun LEE, Chungnam National University
A13Quantification of nanoparticle uptake in human terminal hair follicle in the context of alopecia areata
Abstract
Rebekka CHRISTMANN, University of Saarland
A13bLipid-polymer hybrid nanoparticles (LPNs) for efficient pulmonary delivery of nucleic acids: Lessons learnt from quality-by-design based optimization
Abstract
Kaushik THANKI, University of Copenhagen
A14High density lipoprotein as a novel lymph-directing platform for immunotherapy delivery
Abstract
Gracia GRACIA, Monash University
A15Monocyte-targeted delivery to immune cells using Modified Polysaccharide particles
Abstract
Franklin AFINJUOMO, University of South Australia
A16Development of the first monoclonal antibody for detection of Elastin-like Polypeptides
Abstract
Aida KOUHI, University of Southern California
A17Enhanced oral absorption with nanostructured hydrogel biomaterials
Abstract
Elizabeth LEVY, University of California San Francisco
A18Nanofibrillated cellulose hydrogel as a lyoprotectant in the freeze-drying of HepG2 3D spheroids
Abstract
Arto MERIVAARA, University of Helsinki
A19Evaluation of taste-masking efficiency for the development of an orodispersible film formulation containing ondansetron hydrochloride
Abstract
Wen Chin FOO, National University of Singapore
A20Development of pH-responsive hydrated composite Eudragit-dendrimer formulations for drug delivery
Abstract
Cheryl WONG, National University of Singapore
A21Mesoporous silica nanoparticles (MSN) for antimicrobial peptide delivery: The Influence of PEG crosslinker length on activity
Abstract
Vanitha SELVARAJAN, National University of Singapore
A22Development of peptide-based oral vaccine against hookworm
Abstract
Stacey BARTLETT, University of Queensland
A23Drug delivery to the colon using polysaccharides degraded by the human microbiome and pH-responsive film coatings
Abstract
Michael LANZ, University of Basel
A24Development of microneedles coated with bleomycin for the treatment of skin warts
Abstract
Han Sol LEE, Chungnam National University
A25The use of light as a therapeutic agent for treatment of Diseases
Abstract
Lili DUSE, University of Marburg
A26Human adipose derived mesenchymal stromal cells cultured with wood derived nanofibrillar cellulose
Abstract
Jasmi KIISKINEN, University of Helsinki
A27A fast and precise method for the quantification of PLGA and gelatin based drug delivery systems
Abstract
Aljoscha KÖNNEKE, University of Saarland
A28New methods to evaluate the pharmaceutical equivalence of herbal drugs
Abstract
Quyen TRAN THI, Chungnam National University
A29Development, current applications and future roles of biorelevant two stage in vitro testing in drug development
Abstract
Tom FIOLKA, Goethe University Frankfurt
A30Effects of drug particle size and lipid additives on the degree of drug coating by paraffin wax in spray congealing
Abstract
Hongyi OUYANG, National University of Singapore
A31Influence of polymer structure on controlled release of docetaxel: a comparison of non-bio degradable polymer films for esophageal drug eluting stents
Abstract
Fatemeh FOULADIAN, University of South Australia
A32Design and physicochemical characterization of fenofibrate solid dispersion by supercritical anti-solvent process
Abstract
JungBin AHN, Chungnam National University
A33Effect of calcium ascorbate on the gastric acidity and bioavailability
Abstract
Dong-Hyun KIM, Chungnam National University
A34Homogeneous immunoassay for the detection of EGFR-HER2 heterodimerization on cell surface.
Abstract
Sun Jin KIM, University of Utah
A35Magnesium isoglycyrrhizinate inhibits SMAD2/3 pathway and induced senescence in TGF-?-activated hepatic stellate cells
Abstract
Jie Kai TEE, National University of Singapore
A36Nanomaterials as novel inhibitors that ameliorate fibrosis, adhesion and migration of hepatic stellate cells
Abstract
Fei PENG, National University of Singapore
A37Overexpression of PKCzeta-SUMO mutant in endothelial cells limits angiogenesis in breast cancer cell
Abstract
Naehwan BAEK, Chungnam National University
A38Palmitoylation of the apical sodium dependent bile acid transporter (ASBT;SLC10A2;IBAT)
Abstract
Ebehiremen AYEWOH, University of Maryland
A39Improvement of glucose homeostasis by cucurbitane triterpenoids from the fruits of Momordica charantia through IRS-1 activation in diabetic mice
Abstract
Joo-Hui HAN, Chungnam National University
A40Cytoprotective effects of hypothermia in various acute organ toxicities
Abstract
Yeong Lan TAN, National University of Singapore
A41Systems pharmacological analysis of a combination therapy to overcome HER2 and mTOR-therapies resistance in breast cancer
Abstract
Tanaya VAIDYA, University of Florida
A41bBenznidazole combination therapy with new compound, Neq 821, has potential to protect mice against acute experimental infection of Chagas disease
Abstract
Carla LOPES, University of São Paulo
A42Synthesis of vaccine candidates against Group A Streptococcus
Abstract
Chuankai DAI, University of Queensland
A43Development of an aryloxazole class of Hepatitis C virus inhibitors targeting the entry stage of the viral replication cycle
Abstract
Nicholas KLUS, University of North Carolina Chapel Hill
A44Synthesis and biological evaluation of cationic amphiphilic indoles as antimycobacterial agents
Abstract
Samuel Agyei NYANTAKYI, National University of Singapore
A45Substitution of terminal amide with 1H-1,2,3-triazole: identification of unexpected class of potent antibacterial agents
Abstract
Fangchao BI, Shandong University
A46Design and evaluation of novel beta-hairpin peptides as anti-infectives
Abstract
Nhan Dai Thien TRAM, National University of Singapore
A47Complex speciation modeling to predict the effective concentrations of chelators in human plasma
Abstract
John PRYBYLSKI, University of North Carolina Chapel Hill
A48Development and in vitro Validation of a Computational Model to Predict MRP3 Inhibitors
Abstract
Matthew WELCH, University of Maryland
A49Multi-protein dynamic combinatorial chemistry: A novel strategy that leads to simultaneous discovery of subfamily-selective inhibitors against nucleic acid demethylases FTO and ALKBH3
Abstract
Mohua DAS, National University of Singapore
A50Biomimetic fabrication of DOPA based nano-coatings for stimuli-responsive release system
Abstract
Qinghua LYU, National University of Singapore
A51Effects of mucilage extracts from Pereskia bleo leaves on blood coagulation Time
Abstract
Kamonlawan CHOMCHOPBUN, National University of Singapore
A53Pharmacokinetics study and biodistribution of HCPT-loaded tributyrin emulsion in rats
Abstract
Shili YANG, National University of Singapore
A54In vitro - in vivo correlation for two bioequivalent lidocaine patches under transient heat exposure
Abstract
Sherin THOMAS, University of Maryland
A55Development of mechanism based pharmacokinetics model for implementation of food effect on drug absorption
Abstract
Hyun-moon BACK, Chungnam National University
A56Prediction of human pharmacokinetics of subcutaneously administered depot formulation using MBPK model
Abstract
Fiona Ge GAO, Goethe University Frankfurt
A57Quantification of raloxifene in mouse plasma and tissues by ultra-high performance liquid chromatography-tandem mass spectrometry
Abstract
Sumit BANSAL, National University of Singapore
A58CNS delivery of VX-970: a selective ATR inhibitor for radiosensitization in GBM
Abstract
Surabhi TALELE, University of Minnesota-Twin Cities
A59Elucidation of transporters involved in tissue distribution and urinary excretion of proguanil and cycloguanil in mice
Abstract
Yukana TOMODA, University of Tokyo
A60Brain permeability of Apolipoprotein A1 (ApoA1): Implications for Alzheimer's Disease
Abstract
Andrew ZHOU, University of Minnesota-Twin Cities
A61Time-dependent inhibition of piperine and its impact on the metabolism of carbamazepine
Abstract
Tianjing REN, The Chinese University of Hong Kong
A62Melanosomal drug uptake in the retinal pigment epithelium
Abstract
Laura HELLINEN, University of Eastern Finland
A63Effect of permeability enhancers on paracellular transport of furosemide across Caco-2 cell monolayers
Abstract
Nihan IZAT, Hacettepe University
A64Development and optimization of a direct contact blood brain barrier model for in vitropermeability screening.
Abstract
Kelsey LUBIN, Purdue University

Poster presentations on Fri, 28th Sep

CodeTitleAuthor and affiliation
B1Novel mesoporous nanoparticles for the targeted delivery of anticancer agents to estrogen receptor overexpressing breast cancer
Abstract
Candace DAY, University of South Australia
B2Examining the interactions between mesoporous silica particles and digestion of dietary components
Abstract
Kellie MAY, Monash University
B3Calcium phosphate nanoparticles for the dual delivery of bisphosphonates and pDNA
Abstract
Sofia BISSO, ETH Zurich
B4Doxorubicin-loaded MPI conjugates: Synthesis and in-vitro characterization
Abstract
Ankitkumar PARIKH, University of South Australia
B5Chitosan nanoparticles for oral antigen delivery: a permeability approach.
Abstract
Leah WRIGHT, University of South Australia
B6Sublingual film of salmon calcitonin loaded hydroxyapatite nanoparticles as a non-invasive alternative to parenteral administration
Abstract
Darsheen KOTAK, Institute of Chemical Technology
B7Preparation of microRNA34a-loaded chitosan nanoparticles to upregulate the expression of microRNA-34a in MDA-MB-231 cells
Abstract
Xiaoxia YANG, Shandong University
B8Validation of purification methods for extracellular vesicles
Abstract
Jacopo ZINI, University of Helsinki
B9The microRNA regulatory landscape of MSC-derived exosomes: a systems view
Abstract
Scott FERGUSON, University at Buffalo
B10Development and in-vitro characterization of novel PLGA nanoparticles-Lipid Hybrid (PLH) microparticles for pulmonary delivery of rifampicin
Abstract
Sajedehsadat MAGHREBI, University of South Australia
B11Lymphatic uptake of liposomes after intraperitoneal administration primarily occurs via the diaphragmatic lymphatics and is surface property dependent
Abstract
Given LEE, Monash University
B12Self-nanoemulsifying Drug Delivery System of Resveratrol Trimethyl Ether: Preparation, Characterization and Pharmacokinetic Evaluation
Abstract
Yu DAI, National University of Singapore
B13Skin drug permeation characteristics of oligochitosan- and carboxymethyloligochitosan-carboxymethyl-5-fluorouracil conjugate nanoparticles
Abstract
Mazita MOHD DIAZ, Universiti Teknologi Mara
B14Enhanced photodynamic therapy using nanoencapsulated curcumin
Abstract
Michael R. AGEL, University of Marburg
B15Intratumoral injection of dextran-CpG oligonucleotide conjugates for enhanced immune-stimulation for cancer therapy
Abstract
Hien NGUYEN, University of Otago
B16Kinetic tuning of antibody-biogel interactions for enhanced barrier properties
Abstract
Jennifer SCHILLER, University of North Carolina Chapel Hill
B17PLGA implants for long-acting release of anti-VEGF monoclonal antibody in a rabbit retinal vascular leakage model
Abstract
Jennifer WALKER, University of Michigan
B18Indocyanine green loaded PLGA film coated coronary stents for photo-triggered in situ biofilm eradication
Abstract
Hendrik VÖGELING, University of Marburg
B19Impact of substrate stiffness on dermal papilla aggregates in hydrogel microgels
Abstract
Justin TAN, National University of Singapore
B20Electrospinning of high-content chitosan/polyethylene oxide fibers in GRAS acids
Abstract
Mai BAY STIE, University of Copenhagen
B21Using coiled coil forming peptide to attach a peptide with high affinity
Abstract
Romain LEBOUX, Leiden University
B22Infection responsive delivery of glycoside hydrolase and antibiotic combination
Abstract
Chelsea THORN, University of South Australia
B23Development of the stable long acting injectable parenteral dosage form of Omeprazole for horses
Abstract
Yunmei SONG, University of South Australia
B24In vivo brain delivery of proteins through the BBB
Abstract
Brian KOPEC, University of Kansas
B25Mitigation of the pharmaceutical food effect: Investigation of nanocrystals and lipids
Abstract
Tahlia MEOLA, University of South Australia
B26A high-throughput method to predict the in vivo exposure of different drug delivery systems
Abstract
Caroline ALVEBRATT, Uppsala University
B27Evaluation of effect of minor manufacturing changes and establishment of IVIVC for compositionally equivalent parenteral microsphere drug products
Abstract
Janki ANDHARIYA, University of Connecticut
B28Design of solubility studies in the context of BCS biowaiver monographs
Abstract
Gerlinde PLÖGER, Goethe University Frankfurt
B29Effect of proteins radicals on the stability of polysorbate 80: fatty acid cis-trans isomerization
Abstract
Indira PRAJAPATI, University of Kansas
B30Correlating the effect of magnesium stearate hydrate form, chemical composition and particle size with tablet dissolution
Abstract
Julie CALAHAN, University of Kentucky
B31Effect of polymeric matrix and film formulation on development of verapamil extended release tablet
Abstract
Arnas LAKHIEW, Chulalongkorn University
B32The comparison between co-melted and spray dried clotrimazole-PVP/VA solid dispersions systems
Abstract
Ahmad Ghazali ISMAIL, Universiti Sains Malaysia
B33Formulation development of a recombinant protein based non-replicating rotavirus (NRRV) vaccine candidate: Antigen-adjuvant-preservative interactions
Abstract
Sanjeev AGARWAL, University of Kansas
B34Structurally defined heparan sulfate protects from acetaminophen-induced acute liver failure
Abstract
Katelyn ARNOLD, University of North Carolina Chapel Hill
B35Clioquinol-mediated distribution of zinc and copper regulates the blood-brain barrier expression of breast cancer resistance protein (ABCG2)
Abstract
Chris YAP, Monash University
B36Doxorubicin prodrug that binds apoptotic cells and activated by apoptotic caspase-3 as a component of concurrent chemoradiotherapy for improved therapeutic index
Abstract
Youngseok CHO, Seoul National University
B37Radio-gene therapy targeting RanBP17 gene for down regulation of tumour proliferation in head and neck carcinomas
Abstract
Shashank Reddy PINNAPIREDDY, University of Marburg
B38Effect of autophagy regulation on apoptosis in platelet-derived growth factor-BB stimulated vascular smooth muscle cells
Abstract
Do-Hyung LEE, Chungnam National University
B39Antigen-drug conjugates in the treatment of autoimmunity
Abstract
Matthew CHRISTOPHER, University of Kansas
B40A study of functional analyses for carboxylesterase type 2 isozymes of cynomolgus monkeys
Abstract
Maori TANAKA, Kumamoto University
B41Disease interception of autoimmune disease using soluble antigen arrays
Abstract
Melissa PRESSNALL, University of Kansas
B41bPerception, attitudes and knowledge of pharmacists towards antimicrobial stewardship at nursing homes
Abstract
Aysu SELCUK, National University of Singapore
B42The structure-stability-toxicity relationships of L-DOPA and dopamine thioethers in neuronal cultures
Abstract
Sanzhar KARATAYEV, National University of Singapore
B43Design and comparative evaluation of the anticonvulsant profile, carbonic- anhydrate inhibition and teratogenicity of novel carbamate derivatives of branched aliphatic carboxylic Acids with 4-aminobenzensulfonamide
Abstract
David BIBI, The Hebrew University of Jerusalem
B44Targeted delivery of potent immunosuppressants for treatment of ulcerative colitis
Abstract
Peter KLEINDL, University of Kansas
B45Synthesis and mycobacterial dihydrofolate reductase inhibitory activity evaluation of 4,6-diamino-1,2-dihydro-2-aryl-1-alkyoxyphenyl[1,3,5]triazines
Abstract
Edward LONG, Naitonal University of Singapore
B46Advances in the development of peptidomimetics as potential antimicrobials: A Comparison of Tetrameric and Octameric Peptoids
Abstract
Bettina FLECK, National University of Singapore
B47Calcaratarin D attenuates inflammatory responses through the inhibition of NF-kB activation
Abstract
Thi Ngoc Quy TRAN, National University of Singapore
B48Development of a aacromolecular prodrug of tofacitinib for the sustained treatment of inflammatory arthritis
Abstract
Xin WEI, University of Nebraska Medical Center
B49Polymorphs of an orally available analogue of diethylenetriaminepentaacetic acid: physical and thermal characterization
Abstract
Carla COSTE SANCHEZ, University of North Carolina Chapel Hill
B50Medicinal plants used for erectile dysfunction
Abstract
Valerie SIN, National University of Singapore
B51Reversible single crystal-to-single crystal phase transition with low-temperature induced twinning of diphenhydramine citrate Salt
Abstract
Kunlin WANG, University of Minnesota-Twin Cities
B53Inhibition of human aldehyde oxidase by bazedoxifene and lasofoxifene
Abstract
Shiyan CHEN, National University of Singapore
B54Slow and tight binding inhibition kinetics of CYP17A1 by abiraterone and its active metabolite
Abstract
Eleanor CHEONG, National University of Singapore
B55Human CYP2J2 inhibition by azole antifungals
Abstract
Jacqueline LEOW, National University of Singapore
B56In vitro quantification of sequential metabolism kinetics of ∆9-tetrahydrocannabinol and its metabolites
Abstract
Gabriela PATILEA-VRANA, University of Washington
B57Investigation of the discriminatory power of dissolution specifications for a BCS-based biowaiver via pharmacokinetic modeling
Abstract
Martin HOFSÄSS, Goethe University Frankfurt
B58A pharmacometabolomics approach for predicting tenofovir diphosphate (TFV-DP) concentrations in dried blood spots (DBS)
Abstract
Mustafa IBRAHIM, University of Colorado
B59Pharmacokinetic and allometric ccaling studies of nanoparticle formulations of anthracyclines
Abstract
James BEAUDOIN, University of North Carolina Chapel Hill
B60Tryptophan metabolism and IDO/TDO expression in bladder cancer: A case-control study in Singapore
Abstract
Sze-Han LEE, National University of Singapore
B61Pharmacokinetic disposition of cox-inhibitors for the prevention/treatment of colorectal cancer
Abstract
Glenn LEMMENS, KU Leuven
B62A microfluidic enzymatic digestive system based on chaotic micromixers
Abstract
Pim DE HAAN, University of Groningen
B63Predicting pulmonary pharmacokinetics from in vitro properties of dry powder inhalers
Abstract
Mong-Jen CHEN, University of Florida
B64Primary human hepatocyte spheroids cultured and used in high-throughput screening format
Abstract
Niklas HANDIN, Uppsala University