Ronald T. Borchardt Keynote Lecture
“Getting G Proteins and Lipids Together: Opportunities to Decipher Biology and Make New Drugs”
Patrick J. Casey, PhD
Professor and Senior Vice Dean, Research
Duke-NUS Medical School
Dr Patrick Casey, PhD, is the Senior Vice Dean of Research at the Duke-NUS Medical School. He holds a James B. Duke Professorship of Pharmacology and Cancer Biology at Duke University.
Dr Casey received his PhD in Biochemistry from the Brandeis University in 1986 and did postdoctoral work at the University of Texas Southwestern Medical Center in Dallas. He joined the Duke University Medical Center as an Assistant Professor of Molecular Cancer Biology and Biochemistry in 1990. A recognized authority in the fields of lipid modifications of proteins and in G protein signaling, Dr Casey has received numerous awards for his work including the Established Investigator Award from the American Heart Association in 1992 and the Amgen Award from the American Society of Biochemistry and Molecular Biology in 2000. Dr Casey was the founding Director of the Duke Center for Chemical Biology, established to spearhead interdisciplinary research and training in the application of fundamental chemical principles to the study of biology and the basis of disease and therapies. For his contribution to science, Dr. Casey was elected a Fellow of the American Association for the Advancement of Science in 2012.
In 2005, Dr. Casey added an additional element to his career when he relocated to Singapore to spearhead the development of the Duke-NUS Medical School. As Senior Vice Dean of Research at Duke-NUS, Dr. Casey was the chief architect of the five Signature Research Programs at Duke-NUS: Cancer and Stem Cell Biology, Cardiovascular and Metabolic Disorders, Neuroscience and Behavioral Disorders, Emerging Infectious Diseases, and Health Services and Systems Research. Investigators in these Programs have collectively published more than 3,000 papers, garnered >US$350M in competitive funding, and founded 11 biotechnology companies. Dr. Casey has also played a major role in the Singapore Biomedical Sciences Initiative, serving on advisory committees for the initiative as well as for programs at the Agency for Science, Technology and Research (A*STAR), National Medical Research Council (NMRC) and National Research Foundation (NRF).
Dedicated to training the next generation of scientists and clinician-scientists, Dr. Casey has trained numerous PhD, MD/PhD students and research fellows in his own lab, who occupy positions in academia and biopharma in many continents. Extending his personal experience as a mentor, Dr, Casey has been involved in the development of numerous training programs. He was a founding member, and served as Director for 10 years, of Duke University’s Graduate Program in Molecular Cancer Biology. In Singapore, Dr. Casey led the development of a unique PhD Program in Integrated Biology and Medicine (IBM) at Duke-NUS, an integral component of Duke-NUS’ mission of training translationally-savvy clinicians and scientists.